منابع مشابه
Identifying Obscure Periodic Patterns in Genomic DNA Sequence
Genomic DNA sequence is very abundant in periodic patterns, which play important biological roles, such as gene expression, genome structural stabilization, and recombination. Tandem repeat is a type of periodic patterns and concerns several genetic diseases. Tandem repeat finder (TRF) [1] is one of the widely used programs to find tandem repeats without a priori knowledge. Statistical models a...
متن کاملSpecies-specific patterns of DNA bending and sequence.
Nucleotide sequences in the GenEMBL database were analyzed using strategies designed to reveal species-specific patterns of DNA bending and DNA sequence. The results uncovered striking species-dependent patterns of bending with more variations among individual organisms than between prokaryotes and eukaryotes. The frequency of bent sites in sequences from different bacteria was related to genom...
متن کاملDiscovering approximate-associated sequence patterns for protein-DNA interactions
MOTIVATION The bindings between transcription factors (TFs) and transcription factor binding sites (TFBSs) are fundamental protein-DNA interactions in transcriptional regulation. Extensive efforts have been made to better understand the protein-DNA interactions. Recent mining on exact TF-TFBS-associated sequence patterns (rules) has shown great potentials and achieved very promising results. Ho...
متن کاملEmerging Patterns and Classification Algorithms for DNA Sequence
Existing machine learning methods for classification of DNA sequence achieve good results, but these methods try to express a DNA sequences as discrete multi-dimensional vector, so when the length of the sequences in the DNA sequence database is not fixed or there exists some omitted characters, these methods can not be used directly. In this paper, we define the new support and growth rate of ...
متن کاملDiscovering protein–DNA binding sequence patterns using association rule mining
Protein-DNA bindings between transcription factors (TFs) and transcription factor binding sites (TFBSs) play an essential role in transcriptional regulation. Over the past decades, significant efforts have been made to study the principles for protein-DNA bindings. However, it is considered that there are no simple one-to-one rules between amino acids and nucleotides. Many methods impose compli...
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ژورنال
عنوان ژورنال: Nature Precedings
سال: 2010
ISSN: 1756-0357
DOI: 10.1038/npre.2010.4933